Grants for projects

IMPAVID 2.0

Intelligent Microfabricated Patches as a Drug-Eluting Platform for In Vivo Myocardial Implantation – 2.0
Eco healthcare
Spoke5_IMPAVID2.0image2
Scheda del progetto
Responsabile
P.i Scientific Resp.
Professor Claudia Giachino, University of Torino
Team
Team
Prof. Raffaella Rastaldo
Dr. Roberto Vanni
Dr. Daniela Rossin
Data
Start date
Durata
Duration
12 months
Valore
Approved value
€ 57.600
Investimento
Investment nodes
€ 57.600
Dipartimento
Department
Department of Clinical and Biological Sciences

Heart failure is a complex syndrome with high morbidity and mortality, affecting 64 million people and costing over $100 billion annually. To address this challenge, a biocompatible, resorbable, multilayer cardiac patch has been develped. It mimics the mechanical and anisotropic properties of the myocardium and it is designed to interact at the molecular level with various types of carciac cells. The goals are to reduce technological risks and create a new entrepreneurial reality within the NODES Ecosystem. 

Proof-of-concept studies on pigs and rats have demonstrated the cardioprotective capabilities of the patch, leading to new patentable technologies. The IMPAVID 2.0 projects aims to bridge the gap between research and industry, making the device accessible to patients, delivering economic benefits, and improving quality of life and care. 

The multidiscliplinary team will analyse the economic sustainability of innovation and the risk/benefit ratio, involving the main players in the medtech sector. 

 

 

Contact:

Contact person 
Claudia Giachino 

Email
chiara.giachino@unito.it

Tel
+39 0116705056

 

The goal
Document

The challenge of the project is to develop an effective and innovative solution for the prevention of heart failure, which causes high morbidity and mortality and represents a global unmet clinical need. To address this challenge, the project has developed a microstructured, multilayered, electroconductive, and nano-functionalized patch that: 

  •  emulates the properties of the myocardium 
  •  it biocompatible and resorbable 
  •  facilitates cardiac regeneration 

 

Why is it innovative
Document

This technology offers an innovative approach to heart failure prevention, with significant expected impacts: i) prevention of heart failure onset; ii) improving patients' quality of life; iii) advacement over traditional treatments; iv) cost savings for the health system. 

Impact on the users
Document

The project aims to make the device available to patients, offering a solution that could prevent the onset of heart failure, improve patients' quality of life, surpass traditional treatments, and reduce healthcare system costs.