BRAVE
Scheda del progetto
University of Torino
Prof. Enrico Bollo
Dr. Marcello Pallante
Dr. Annapaola Parrilli
The BRAVE project aims to validate an innovative biodegradable device for tendon rupture repair, eliminating the need for sutures. Developed in Turin, it will be tested on horse tendons as a model for the human Achilles tendon. Expected outcomes include the implementation of the new technique, mechanical and micro-vascular assessments, and cell viability tests. The primary beneficiaries are both human and animal patients with tendon ruptures, as well as medical and veterinary professionals. This device promises to enhance quality of life and advance research in orthopedic surgery and regenerative medicine.
Contact:
Contact person
Andrea Bertuglia
Email
andrea.bertuglia@unito.it
Tel
+39 0116709058
+39 3470034742
Revolutionizing the method of repairing tendon ruptures, which is currently based on outdated suture techniques, despite technological advancements in orthopedic surgery in recent years. The goal is to validate a new biodegradable device for tendon repair, eliminating the use of sutures in both human and veterinary applications. Clinically optimizing the device developed by a research group in Turin and its associated applicator is also a priority.
Optimization of the implantation technique using the superficial flexor tendon of the horse's phalanges as a preclinical experimental model for the human Achilles tendon. Assessment of the mechanical performance of the device through uniaxial tensile testing and comparison with the results of traditional tenorrhaphy. Evaluation of the device's impact on the micro-vascularization of the tendon using advanced imaging diagnostics and in vitro cytotoxicity tests to assess its effect on cell viability.
Improvement of the quality of life for people and animals suffering from tendon ruptures through the introduction of a new biodegradable device that offers advantages over traditional suture techniques. Contribution to the field of orthopedic surgery and regenerative medicine.