Industrial PoCs

The MEDASSIST project aims to develop a remote a telehealth assistance device using a Head Mounted Display (hmd) with Near-to-Eye (NTE) binocular display. This device will alow healthcare providers to exchange video and vital signs with specialized professionals remotely, enhancing access to care in remote areas or emergency situations. In addition, it will facilitate timely and high-quality medical consultations, reducing costs and optimizing disease management. Overall, significant advancements in healthcare efficiency and quality are anticipated, with reduced wait times and personalized care delivered promptly. The project leader, Illogic, specializing in digital creativity, possesses expertise in the entire software development lifecycle, ensuring effective design, planning and development.     Contact: Guido Sodano sodano@illogic.xyz      

The MoPaVIoT project contributes to innovation in digital healthcare by developing an innovative wearable device for tele-monitoring, focusing on vital parameters such as body temperature, oxygen saturation and blood pressure. The company Tecnica Scientifica Service already a manufacturer of CE-marked Medical Devices, will coordinate all project phases, including certification and commercialization. Politecnico di Torino (LISiN - Laboratory of Neuromuscular System Engineering - Department of Electronics and Telecommunications) will contribute through a research project to the architectural and project choices, providing specific expertise in the field of Medical devices, particularly electromedical devices.    Contact: Alessio Petricca a.petricca@tssmedical.com   

The NUTRI.AGE project aims to create synergies between companies and academic research to develop solutions for the silver economy and elderly health. It focuses on creating digitally monitored processes and products, with the goal of testing the applicability of probiotic strains associated with bioactive peptides and ''green'' solutions through in vivo trials.  SYNBALANCE specialized in fermentation and probiotic formulation, will collaborate with COSTANTINO & C. S.p.A to select biomasses, the preparation of bioactive ingredients aimed at optimizing the effectiveness of probiotic strains and the safety assessment of bioactive ingredients. PHOIBOS, the third partner, will apply electronic and information technologies to create innovative control system and measurements and implement analysis and data collection algorithms in various experimental contexts.    Contact: Patrizia Malfa p.malfa@synbalance.care  

The PREDIBIO project aims to revolutionize the approach to prevention, diagnosis, and treatment of diseases associated with Bipolar Disorder (BD) through advanced omics analyses.  The objective is to identify new biomarkers for the early diagnosis of Bipolar Disorder (BD), enabling timely interventions and non-invasive personalized therapies. The Consorzio Piemontese per la Prevenzione e Repressione del Doping e di Altri Usi Illeciti dei Farmaci (CAD) will lead the project with experience in clinical and biological chemistry with innovative analytical methodologies. The center Villa di Salute - Casa di Cura Neuropsichiatrica Trofarello (ORPEA) will contribute, as an end user, by providing sampling and clinical validation. In parallel, DISAT and the UNITO Department of Chemistry will bring scientific and technological expertise, developing analytical methodologies and managing data.   Contact: Paolo Garofano  paolo.garofano@antidoping.piemonte.it  

The TEPSIM project focuses on optimizing the transarterial embolization (TAE) procedure for the treatment of liver cancer that involves blocking the blood supply to the tumor. The approach aims to effectively plan the embolization procedures using specific 3D virtual models tailored to the patient. The personalized medicine software platform developed by Medics will allow extraction and visualization of 3D models of the liver and intrahepatic vascular structures from medical imaging data. The OdR will contribute as a specialist consultant for creating personalized models of transport phenomena in the hepatic system based on hemodynamic parameters measured in vivo.    Contact: Giuseppe Isu giuseppe.isu@medics3d.com   

The YOGA project aims to create personalized therapies for osteoarthritis by combining in vitro diagnostics and artificial intelligence. It will utilize complex cell cultures in the cartilaginous environment, analyzing inflammatory markers with microfluidic technologies.     The data will be stored in a database for the development of predictive models of therapeutic efficacy. The partnership involves two SMEs, Trustech Diagnostics that will contribute expertise in the design of miniature diagnostic methods and EnginSoft with will bring contribute with global digital skills. The project will also benefit from the support of Tissuegraft as a consultant for biological characterization.    Contact: Laura Maria Boschis  laura.boschis@trustech.it   

The MASTRO project aims to utilize additive manufacturing with Ti6AI4V (TiAm), which offers good mechanical properties and biocompatibility reducing its toxicity, to create acetabular components for total dual-mobility hip prostheses with reduced risk for the patient, and to address the criticalities of currently used Chromium-Cobalt (CoCr) alloys currently used.  Using the concept of ''patient-matched device'', the goal is to create an adaptable product starting from mass production, with the capability for secondary modifications to ensure optimal adaptation to the patient's anatomy.   The project also includes the development of an automatic patient adaptation algorithm (3AP) for large-scale design, addressing current global regulatory challenges.  MT Ortho S.r.l. leads the project with the support of the University of Messina, Politecnico di Torino and IRCSS Ospedale Galeazzi Sant'Ambrogio.    Contact: Gaetano Sorano info@mtortho.com   

The ROBO-HOSPITAL project aims to develop an integrated robotic system to manage test tubes and biological samples in the healthcare context with particular focus on sample preparation operations post-collection. Key features of the project include precise sample handling, automatic tracking, safe packaging, sanitizing of test tubes and transport containers, as well as advanced connectivity features to integrate laboratory information systems and axchange information related to the biological sample.  This means: increased operational efficiency, sample safety, process transparency and a reduction in non-conformity errors.  Presented by ROBOSAN S.r.l., the project aims to automate and simplify the management and preparation of biological samples, helping to optimize health resources and ensure a more reliable and secure service for all patients.    Contact: Vittorio Trifari  admin@robosan.it  

The project aims to develop a robotic system characterized by excellent manipulation capabilities and sized for implementation in a cubesat, with the purpose of making berthing, servicing and manufacturing maneuvers possible in space. A system will be developed consisting of a planar robotic arm with an end-effector with one or more degrees of freedom and equipped with an electro-adhesive gripper, with increased dexterity due to cooperation between robot and cubesat control.   Contacts: Camilla Conti, camilla.conti@adaptronics.it  

Unmanned Aircraft Systems (UAS) can be used for a wide range of industrial and civil applications such as land monitoring, precision agriculture, infrastructure inspection, short- to medium-range transportation, and surveillance, reducing operator risk, time, and cost. This project aims to develop, implement and test in an operational environment a fuel cell power system and integrate it on an existing multi-engine drone to extend its flight range.   Contacts: Salvatore Mafrici, salvatore.mafrici@punchtorino.com  

DT4energy.com aims to provide an intelligent digital solution for sustainable and resilient community development, particularly for planning renewable energy communities (RECs) in foothill and mountainous contexts, from large-scale planning down to individual buildings. Specifically, the project aims to develop innovative tools to enhance energy flexibility on the demand side and to provide services to the community energy manager. The underlying idea is to develop a prototype through the creation of a Digital Twin—a virtual representation—of a limited portion of territory, and to develop innovative smart solutions and sensors for data collection, community monitoring, and the implementation of management and control strategies.     Contact: Mauro Demarziani     m.demarziani@aegcoop.it     3490660184

The GAIA project aims to develop a federated meta-platform software for the management of multi-vector renewable energy. The goal is to promote innovative solutions to create Alpine energy communities, thus encouraging the optimized use of renewable sources and sustainable energy resource management at various levels. The meta-platform facilitates data and information exchange among various stakeholders in the mountain energy community (e.g., energy resellers, distributors, or other market actors), enhancing integration, collaboration, and effectiveness in energy management. Ultimately, the project supports the development of new data-driven services and business models.     Contact: Alessio Viticchié a.viticchie@awaves.it   

The GEEDI project aims to develop a software service platform that supports energy planning and retrofitting processes in the building sector, with a special focus on mountainous regions, to promote sustainable development. Leveraging data analytics techniques, the services aim to facilitate the digitalization and enhance the energy characterization of existing building stock, from assessing the current state to defining scenarios for potential retrofitting interventions. Ultimately, GEEDI will provide operational tools to support energy design, enabling tracking over time of the implementation of strategies and retrofitting interventions aimed at improving building energy performance, as well as monitoring the achieved results. Through the use of Building Information Modeling (BIM) tools and by collecting and storing files of various types that can be updated over time, the platform will enable the creation of a digital logbook for each building.       Contact: Fabio Valeggia f.valeggia@edilclima.it

Given the current condition of Alpine regions, particularly the cryosphere, due to climate change, the HIKE project aims to monitor high-altitude nivometeorological and glacial dynamics. It plans to achieve this by designing integrated systems for innovative monitoring of solid precipitation and digital optical analysis of glacial dynamics and snow cover. Additionally, HIKE aims to implement automated procedures for data quality control and cross-validation, along with developing a web platform for sharing acquired data and information. Activities will focus on the Monte Rosa massif, a hotspot for water-based economic activities (e.g., ski resorts, hydroelectric power), with the prospect of developing digital systems and tools applicable to other mountainous contexts as well.       Contact: Mauro Reguzzoni mreguzzoni@hortus.it

The MAPP project aims to envision a new model of immersive museum experience centered around the relationship between tourists and mountain parks, akin to urban museums. Through a physical, digital, and participatory approach, the goal is to develop a digital ecosystem to enhance outdoor tourism. This model is based on monitoring tourist flows and simultaneously engaging tourists actively during their visit through an app. The app facilitates collaboration with park authorities in the conservation process and reporting any trail anomalies. Additionally, Visual Place Recognition technology is utilized to enhance the experience.     Contact: Paolo Landolfo prologic@pro-logic.it   Photo from https://it.freepik.com/

The idea behind the PERFORM project is to optimize the management of energy resources in mountainous environments, focusing on the production and transportation of energy from renewable sources. It addresses two interconnected challenges. The first involves three-dimensional modeling of slopes to assess the efficiency and optimal exposure for photovoltaic installations. The second challenge concerns facilitating energy transportation via overhead power lines, starting with enhancing the three-dimensional terrain model (including vegetation footprint and its predictive growth model). Both services are made scalable and analyzable using a platform called Skymetry, which provides a wide range of services for generating 2D/3D models of terrain and infrastructure.     Contact: Luca Olivotto olivotto@digisky.it

The project named PolarALP aims to develop industrially and test in operational environments a prototype of an innovative rapid alert system based on fiber optic sensors for mitigating risks associated with mass transport phenomena such as avalanches, debris flows, and rockfalls. Due to climate change, these events are becoming more frequent and destructive as the intensity of triggering factors continues to increase. These events generate characteristic vibrations during their propagation that can be promptly identified by fiber optics before reaching at-risk infrastructure. In this project, the initial focus is on developing algorithms for accurately identifying events and establishing the operational logic of the rapid alert system. Subsequently, the plan is to design, construct, and integrate the components necessary to create a complete prototype of the system. This prototype will be tested in a canyon in Valle d'Aosta, where such mass transport phenomena typically occur and propagate. Based on the results obtained from the experimental phase, specifications for industrializing the system will be finalized.     Contact: Francesco Antolini francesco.antolini@geo-solving.com

The SAD project aims to develop strategies and solutions for fire-prone areas to enable timely detection of fire outbreaks, facilitating rapid and effective response efforts. The idea is to establish surveillance and monitoring systems through the integration of Internet of Things (IoT), Computer Vision, and Artificial Intelligence technologies. Specifically, the goal is to create a monitoring network where AI vision algorithms transform ordinary cameras into sentinels capable of swiftly detecting smoke plumes and flames in outdoor environments. This generates data and alerts that automatically feed into decision support tools already implemented at national and European scales.     Contact: Paola Allamano paola.allamano@waterview.it

The SERENA project focuses on the development of innovative digital pressure sensors for pressurized pipelines. Specifically, the company aims to develop a new pressure sensor that can be externally applied to any type of pipeline. This sensor measures expansion resulting from the pressure level inside the pipe, thereby determining pressure and stress externally without the need for drilling or flanged measurement stages on the conduit. This approach avoids the use of seals and prevents leaks. The external application also simplifies sensor installation on existing systems. The sensor's long-range radio interface (LoRa) enables the implementation of control algorithms, monitoring, and predictive maintenance of hydrogen distribution networks and water distribution networks, even in remote areas such as mountainous or hilly regions. Gaseous hydrogen, being a very small molecule, presents challenges in preventing leaks, which complicates its use as an energy carrier in mountainous areas or for transalpine pipelines. Existing water networks, on the other hand, are often old and prone to significant leakage, a concern exacerbated in recent years marked by droughts, especially in the Alpine region. Operators will be able to monitor the network with minimal operating costs, using both standard data analysis (inferential statistics) and machine learning/artificial intelligence algorithms.     Contact: Giuseppe Tussiwand gt@hapticasensing.com

The SMARTIDROALPI project addresses the water and energy needs of small mountain communities (refuges, mountain pastures, small villages) by developing innovative digital solutions and tools for the efficient integration of intermittent renewable sources (solar, wind, etc.) into their energy systems. Specifically, the project aims to prototype a TRL6-level digital micro-hydropower generation system interfaced in parallel with other electricity production sources such as photovoltaic solar and small wind turbines.     Contact: Enrico Ainardi enrico.ainardi@irem.it

EURIX with the WOW project proposes a human-in-the-loop solution to support individual work and productivity in mountain environments through teleworking, co-working, and indoor work. The WOW solution automatically collects both objective data on Indoor Environmental Quality (IEQ) using innovative IoT infrastructure, and subjective data on workers' well-being and productivity. If well-being and productivity indices deviate from recommended values, the WOW solution will provide useful insights to workers to enhance working conditions and productivity. Machine Learning models capturing the relationship between productivity and collected data will generate these insights. The end user, Alta Langa Mountain Union, will contribute to validating the system in a real operational environment and enhancing the solution's impact on the territory.     Contact: Massimo Amerio amerio@eurixgroup.com

The requested service aims to study and develop a digital tool for decision support (DSS) that allows comparing the performance and impacts of different types of Demand Responsive Transport System (DRTS - on-demand transport service). The area and implementation objectives (e.g. target users) are taken into consideration to provide transport operators with information useful for identifying the most effective and efficient on-demand service models. Furthermore, the operational, environmental and social impacts that the different types of DRTS can have are identified, depending on the geographical contexts. Finally, the definition of a digital catalog for the classification of DRTS is envisaged, which includes descriptions of services, characterizing parameters, enabling technologies, examples of best practices and sources.       Contact: Filippo Beltrani filippo.beltrani@distribus.it

The SecureFWA service aims to make Fixed Wireless Access (FWA) networks, the main Internet access technology in mountain areas, safer and more easily maintainable. The difficulty of accessing the sites where the nodes are installed, especially in adverse climatic conditions, is the main maintenance problem of FWA networks and, in this sense, the project intends to solve it by using LoRaWAN technology to create an alternative communication network, such as backup for FWA networks, with the aim of making them more robust and secure. Using LoRaWAN, nodes will be able to communicate their configuration even in the event of low available power, thus allowing technicians to plan maintenance in advance. Furthermore, if the FWA network nodes stop functioning, the LoRaWAN network would still be able to provide network access to operators.       Contact: Giancarlo Zamboni giancarlo.zamboni@halservice.it

ARBOREA is an innovative platform which, operating on the double track of social and territorial innovation, promotes the development and valorisation of innovative models for the management of mountain forest heritage, the related public services and the transformation of green infrastructures into a valorisation tool economical for the owners. ARBOREA, in fact, makes it possible to simplify the entry of small owners into the market for the voluntary exchange of carbon credits through the integrated management of the service cycle, from the analysis and quantification of the CO2 removed from a forest area to the management of the exchange between a landowner and a private company for emissions offset projects. In this way, the project aims to promote better management of forestry assets, reduce deforestation and implement a new model to analyze the value of a forest in an integrated way.       Contact: Mauro Manente mauro.manente@latitudo40.com

The project promotes sustainable and assisted tourism in mountain areas, helping to enhance and preserve the natural and cultural resources of these regions and encouraging the social inclusion of the elderly by encouraging an active lifestyle and improving people's health. It involves the introduction of an innovative technological solution that combines sensors, mobile apps and real-time monitoring to address the challenges of the tourism sector and the aging population by promoting the digitalisation of mountain areas in order to address demographic, economic challenges and environmental issues of these territories.       Contact: Paolo Casacci paolo.casacci@liferesult.it  

The project was created to support the mobility of people in Low Demand Areas (ADD), i.e. those areas where problems related to citizens' travel and the supply of Local Public Transport (LPT) coexist. In those specific areas, given the low population density and the geographical distance, the use of private or shared vehicles is necessary. The project therefore aims to strengthen the transport system, providing flexible, on-demand and dynamic services for ADDs. To do this we will start from the study of the main players in the transport system and technologies, we will define the mathematical models and artificial intelligence algorithms and we will develop an innovative Cloud platform and a mobile application to meet the needs of different users ( residents, tourists, business travelers, commuters, etc.). Thanks to these innovative solutions it will be possible to optimize travel, save time and resources and enrich the city's transport system, with an inclusive and environmentally friendly perspective.       Contact: Thomas Tschurtschenthaler tt@famassystem.it

The project is divided into the development of solutions, devices, tools and IT services aimed at supporting activities in the field of remote working. The unifying element is the use of digital technologies to improve business performance by introducing conciliatory policies. The project intends to achieve a "virtualization and digitalization of production processes" in which the various actors involved (employees, collaborators, client companies) can interact and contribute to building process sections. Remote working, in addition to meeting employee conciliation needs, allows you to manage peaks in demand thanks to the possibility of activating additional collaborators and professionals. The creation and making available of the SWIM platform could also contribute to containing the phenomenon of depopulation of Apulian municipalities, especially those located in internal and marginal areas.       Contact: Giovanni Tricarico tricarico.g@confcooperative.it

The project intends to activate a series of "flexplaces" in mountain communities, places for remote working and interaction that are economically, socially and environmentally sustainable, through the creation of a digital supply chain that involves the entire territory. The objectives are: to revive the mountain villages by attracting the so-called. “digital nomads”; make physical infrastructure and digital systems available for remote working and leisure; collect, analyze and release environmental, energy and social data on the use of "flexplaces". The sustainability of the project is monitored through the virtual assistant Dorota, a precious AI resource designed for the retrieval, processing and release of data deriving from the use of "flexplaces" in Digital Mountain Communities.   Contact: Ezio Gaude eg@ultraspazio.com +39 379 1603774

MOUNTAINEER is an innovative platform to support the digital and sustainable transition of mountains through a new model for managing their water, forestry and agricultural resources and for risk mitigation. The platform will allow energy industries and institutions to evaluate and plan the availability of water resources on a regional basis, starting from the monitoring of snowfall. At the same time, the platform will allow small businesses and agricultural owners to receive this information and forecasts and enrich them with observations and analyzes relating to their specific location. The platform will therefore serve the dual role of data analysis and dissemination. To enrich the information platform, specific acquisitions from stratospheric aerial platforms will be provided which will complement, in some cases replacing, satellite ones.   Contact: Victor Miherea victor.miherea@stratobotic.com +393489225275

The project aims to develop an innovative methodology for monitoring gravitational phenomena in mountain areas, in particular for rapid flow phenomena. To this end, contact was made with the Municipality of Bardonecchia (TO) for the implementation of the system along the Frejus torrent basin. The intent is to obtain a functional and as economical tool as possible through the installation of a cloud of low-cost IoT sensors in the area subject to gravitational phenomena which communicates the data in real time to a web-based platform. It envisages, on the one hand, the creation of the Digital Twin of a phenomenon of instability in a mountain area and, on the other, the possibility of viewing the data and deviations recorded by the IoT sensors installed in situ using an augmented reality viewer. This allows a significant increase in the level of safety for the operators involved in the measurement phases, as well as being able to remotely monitor the phenomenon. The collection of data from the sensors positioned in the field will be directed to a web-based platform from which the digital twin and the augmented reality viewer will continuously acquire information.   Contact: Maximiliano Ricci     maximilianoricci@emisfera.it       3496855419

The Eoliann project, with the support of the Links Foundation, aims to estimate the landslide risk across the entire territory of the Piedmont region and to evaluate the impact that this type of risk can have on the road infrastructure. To achieve this objective, physical and data-driven modeling techniques (Artificial Intelligence) will be used based on the use of satellite images and data from different sources, which allow changes in meteorological, hydrological and environmental conditions to be better taken into account. The main objective is to provide support to the managing bodies and competent authorities in prioritizing interventions on the road sections (or logistics chains) with the greatest climate risk and the highest potential economic losses. After the research phase, the models will be adapted to a specific context and validated with the collaboration of the Piedmont Region (end user).   Contacts: Giacomo Di Fuccia – Project Coordinator     giacomo.difuccia@eoliann.com     Federico D’Albenzio – Business Developer federico.dalbenzio@eoliann.com +39 3423386840

The project intends to propose a new model of mountain regeneration by developing a pilot example in mountain areas in the municipality of Rassa (VC). Thanks to the new digital tools available today, as well as the use of renewable energy sources, it intends to bring a stable human presence back to the mountains, which perpetuates traditional production and land and landscape management activities, while at the same time allowing for greater use and diffusion. Furthermore, the project intends to promote biodiversity by going beyond the strategy of mere conservation and proposing a scientifically validated land modification action aimed at the regeneration of historic habitats that are disappearing.   Contact: Federica Barone federica.barone@neorisorse.net 3485412416

Volta Structural Energy Srl develops an innovative structural battery technology: multifunctional elements capable of supporting high mechanical loads and storing and releasing electrical energy like ordinary batteries. This technology is ideal for maximising the energy density and autonomy of electrically powered platforms and compatible with all non-stationary applications, from space to aeronautics to land and sea mobility.    Contacts: Chiara Mirani, Volta Structural Energy srl  

The service consists in consulting for the management and exploitation of Adaptronics' intellectual property in the space sector, with particular regard to hardware and software technologies that can be implemented in cubesats, and the management of data collected by Adaptronics' sensor and digital twin technology. In addition, coaching activities are planned for the management of partnerships and customer relationships on IP and confidentiality aspects.   Contacts: Camilla Conti, camilla.conti@adaptronics.it  

The activities proposed in the service concern aspects related to the regulations, authorisations and certifications necessary for the installation, commissioning and operation of an experimental micro hydrogen refuelling station for hydrogen powered land vehicles. The support activity will focus on the following issues Identification and analysis of permitting procedures for the installation the use of the refuelling system; Consulting activities on the applicable product and refuelling system regulations/technological standards for the installation and operation of the system; Assistance in the identification of accredited certification bodies; Assistance in risk assessment and self-assessment of development phases.   Contacts: Federico Bassano, federico.bassano@holdim.it    

Consulting service aimed at the development and implementation of a Business Process Management platform that enables the digitalization of business processes in the area of resource efficiency, both in material terms and greater trust. The transformation impacts the entire value chain and the business potential of mobility systems, from vehicles for individual passenger transport to new paradigms of indoor and outdoor transportation for industrial and civil logistics.   Contacts: Stefano Gussoni, stefano@gussoniconsulenze.it    

PEARL plans a radical reformulation of the network architecture in charge of managing autonomous fleets, combined with the realisation of a dedicated Control Room, characterised by an optimal level of security, intended for the efficient monitoring and control of the mentioned fleets, even in the absence of connectivity.   Contacts: Diana Cimpoesu, Eurofork, diana.cimpoesu@eurofork.com    

The project aims to develop a state-of-the-art on-board computer for satellite builders and operators, with the goal of enabling autonomy for satellite operations directly in orbit. With this integrated computer, the satellite will be able to autonomously manage its on-board resources and work plan, thereby optimizing communications with Mission Control Centers, the load on assigned teams, and the costs incurred by operators. Thanks to the advanced learning algorithms at the heart of the system, the satellite will also be able to optimize data acquisition and processing, as in the case of Earth Observation (EO) missions, facilitating applications such as environmental monitoring, land resource management and disaster response. The result will be an integrated solution that includes hardware, middleware and software   Contact: Alessandro Benetton alessandro@aikospace.com

The SSSMP project intends to develop an integrated digital platform with the aim of 1. Reducing the number of victims of road accidents by speeding up the detection and reporting of accidents; 2. Take advantage of the large amount of underground optical fibres (already laid and still unused) to turn them into active accident detection sensors. 3. Integrate data networks and road technologies such as charging stations, traffic lights, road cameras and speed cameras into the platform to provide a single point of monitoring and self-diagnosis of the entire ecosystem.   Contacts: Giulio Valzolgher, gvalzolgher@fastalp.it   

The TRINITÀ project aims to develop a new therapeutic and diagnostic agents for the treatment of oncological pathologies with a high need of cures. The collaboration between the two partner Dompé Farmaceutici and ViroStatics, supported by the scientific experience of University of Pavia, will focus on the synthesis, preclinical characterization, and afvancement of the development of innovative drugs, the development of new personalized drug delivery systems, and advanced diagnostic probes using state-of-art digital technologies. The relevant oncological pathologies of interest in the project include ductal adenocarcinoma, lung cancer, malignant pleural mesothelioma and breast cancer resistant to CDK4/6 inhibitors.     Contact: Samuele Lillini  samuele.lillini@dompe.com